| A two-year carcinogenicity study was also conducted in male and female mice at oral doses up to 100Â mg/kg/day (approximately 11 times the maximum recommended human oral dose based on mg/m 2). The metabolism of Copanlisib can be decreased when combined with Erythromycin. Selegiline may increase the hypotensive activities of Captopril. No such effect was seen at 3000 mcg/kg (approximately 1600 times the MRHDID on a mcg/m 2 basis). Colospa 135Mg Tablet can only be prescribed to children who are above the age of 10 years. The metabolism of Cholecalciferol can be decreased when combined with Verapamil. |
