The serum concentration of Hydrocodone can be increased when it is combined with Clarithromycin. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects. Also tell your doctor if you have ever had to stop taking a medication for mental illness due to severe side effects and if you plan to work with organophosphorus insecticides (a type of chemical used to kill insects). Cano-Marquina A, TarÃn JJ, Cano A (May 2013). Hepatic impairment—Patients with hepatic impairment have developed cases of metformin-associated lactic acidosis. Danazol is a CYP3A4 inhibitor and may inhibit the metabolism of atorvastatin, a CYP3A4 substrate. |