In fact, hypokalemia is one of the indications for potassium-sparing diuretic therapy. Ziconotide may increase the central nervous system depressant (CNS depressant) activities of Azelastine. Ask your pharmacist to recommend a suitable remedy. The metabolism of Cabergoline can be decreased when combined with Sildenafil. Other drugs may interact with Toprol-XL, including prescription and over-the-counter medicines, vitamins, and herbal products. Geriatric Use: No overall differences in efficacy or safety vs younger patients, but greater sensitivity of some older adults cannot be ruled out (8. |