The treatment duration for letrozole is only five days. Use a moisturizer like Differin Soothing Moisturizer. Doses up to 750 mg PO given 3 to 4 times per day may be given for severe muscle spasm, but reduce when possible to lowest effective dose. A study evaluating genotoxicity of efavirenz in mice noted DNA damage in brain cells after daily dosing for 36 days; no damage was seen in liver, heart, or peripheral blood cells. Additionally, the following adverse reactions were reported in ≥1. Polymyxin B: (Moderate) It was previously thought that antibiotics may decrease the effectiveness of oral contraceptives containing estrogens due to stimulation of estrogen metabolism or a reduction in estrogen enterohepatic circulation via changes in GI flora. |