In studies in which pregnant rats were given nebivolol during organogenesis, reduced fetal body weights were observed at maternally toxic doses of 20 and 40 mg/kg/day (5 and 10 times the MRHD), and small reversible delays in sternal and thoracic ossification associated with the reduced fetal body weights and a small increase in resorption occurred at 40 mg/kg/day (10 times the MRHD). However, since we live abroad none of the doctors are aware or familiar with the Ayurvedic ingredients used in Septilin and hence unable to guide us about it. The metabolism of Prochlorperazine can be decreased when combined with Clomipramine. The company practice of sending out spam emails and its unrealistic advertising campaign has prompted negative feedback from men who bought the product. The metabolism of Clevidipine can be decreased when combined with Ketoconazole. In epilepsy, it may be used for those with partial seizures. |